Details
1-(3-Fluorophenyl)piperazine Good Supplier In Bulk Supply High Purity 3801-89-6
- Molecular Formula: C10H13FN2
- Molecular Weight: 180.225
- Appearance/Colour: liqui
- Boiling Point: 301.664 °C at 760 mmHg
- PKA: 8.85±0.10(Predicted)
- Flash Point: 136.242 °C
- PSA： 15.27000
- Density: 1.113 g/cm3
- LogP: 1.62910
1-(3-Fluorophenyl)piperazine(Cas 3801-89-6) Usage
InChI:InChI=1/C10H13FN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
3801-89-6 Relevant articles
Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors
Zhou, Hua,McGowan, Meredeth A.,Lipford, Kathryn,Christopher, Matthew,Fradera, Xavier,Witter, David,Lesburg, Charles A.,Li, Chaomin,Methot, Joey L.,Lampe, John,Achab, Abdelghani,Shaffer, Lynsey,Goldenblatt, Peter,Shah, Sanjiv,Bass, Alan,Schroeder, Gottfried,Chen, Dapeng,Zeng, Haoyu,Augustin, Martin A.,Katz, Jason D.
, (2020)
A high-throughput screening (HTS) campai...
Evaluation of substituted n-phenylpiperazine analogs as D3 vs. D2 dopamine receptor subtype selective ligands
Lee, Boeun,Taylor, Michelle,Griffin, Suzy A.,McInnis, Tamara,Sumien, Nathalie,Mach, Robert H.,Luedtke, Robert R.
supporting information, (2021/06/14)
N-phenylpiperazine analogs can bind sele...
MONOACYLGLYCEROL LIPASE INHIBITORS
-
Paragraph 0111-0112; 0141; 0153-0154; 0161-0162, (2021/09/09)
Provided are compounds of formula (I), o...
PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
-
Page/Page column 60, (2019/07/13)
Provided herein is compounds of formulas...
3801-89-6 Process route
-
-
110-85-0
piperazine
-
-
625-98-9
3-chlorofluorobenzene
-
-
3801-89-6
1-(3-fluorophenyl)piperazine
| Conditions | Yield |
|---|---|
|
With
tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; ruphos;
In
1,4-dioxane;
at 100 ℃;
for 1h;
|
51.9%
|
-
-
951626-85-0
tert-butyl 4-(3-fluorophenyl)piperazine-1-carboxylate
-
-
3801-89-6
1-(3-fluorophenyl)piperazine
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
1,4-dioxane;
at 20 ℃;
|
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 2h;
|
3801-89-6 Upstream products
-
372-19-0
meta-fluoroaniline
-
821-48-7
bis-(2-chloroethyl)amine hydrochloride
-
1073-06-9
3-fluorobromobenzene
-
951626-85-0
tert-butyl 4-(3-fluorophenyl)piperazine-1-carboxylate
3801-89-6 Downstream products
-
72222-97-0
3-[4-(3-fluoro-phenyl)-piperazin-1-yl]-2H -benzo[1,4]oxazine
-
57962-06-8
2-{2-[4-(3-fluoro-phenyl)-piperazin-1-yl]-ethyl}-quinoline
-
78069-82-6
1-(3-Fluoro-phenyl)-4-(3-nitro-pyridin-4-yl)-piperazine
-
137965-89-0
1-{5-[4-(3-Fluoro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one
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