1-benzyl-4-(methoxymethyl)-N-phenylpiperidin-4-amine
- CasNo：61380-02-7
- purity：99%
Details
Factory Supply industrial standard 1-benzyl-4-(methoxymethyl)-N-phenylpiperidin-4-amine 61380-02-7 In Stock
- Molecular Formula: C20H26 N2 O
- Molecular Weight: 310.439
- Vapor Pressure: 1.12E-07mmHg at 25°C
- Boiling Point: 432.3°C at 760 mmHg
- Flash Point: 215.2°C
- PSA： 24.50000
- Density: 1.096g/cm3
- LogP: 3.79060
1-benzyl-4-(methoxymethyl)-N-phenylpiperidin-4-amine(Cas 61380-02-7) Usage
InChI:InChI=1/C20H26N2O/c1-23-17-20(21-19-10-6-3-7-11-19)12-14-22(15-13-20)16-18-8-4-2-5-9-18/h2-11,21H,12-17H2,1H3
61380-02-7 Relevant articles
SUBSTITUTED N-(2-(AMINO)-2-OXOETHYL)BENZAMIDE INHIBITORS OF AUTOTAXIN AND THEIR PREPARATION AND USE IN THE TREATMENT OF LPA-DEPENDENT OR LPA-MEDIATED DISEASES
-
Page/Page column 36, (2015/12/17)
The present invention relates to compoun...
SUBSTITUTED 4-AMINO-PIPERIDINES
-
Page/Page column 25, (2010/02/17)
The present invention relates to new sub...
A facile method for preparation of [2H3]-sufentanil and its metabolites
Srimurugan, Sankareswaran,Murugan, Kaliyappan,Chen, Chinpiao
experimental part, p. 1421 - 1424 (2010/06/14)
An improved process for the synthesis of...
IMPROVED METHOD OF MAKING SUFENTANIL
-
Page/Page column 4; 8-9, (2010/11/29)
The present invention relates to a proce...
61380-02-7 Process route
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-
61086-04-2
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol
-
-
74-88-4
methyl iodide
-
-
61380-02-7
4-(methoxymethyl)-N-phenyl-1-(phenylmethyl)-4-piperidinamine
| Conditions | Yield |
|---|---|
|
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol;
With
sodium hydride;
In
tetrahydrofuran;
at 20 - 50 ℃;
methyl iodide;
In
tetrahydrofuran;
at 0 - 20 ℃;
|
83%
|
|
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol;
With
sodium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 2.83333h;
methyl iodide;
In
tetrahydrofuran;
at 20 ℃;
for 3.41667h;
|
80.5%
|
|
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
methyl iodide;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
|
67%
|
|
In
N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; water; ethyl acetate; mineral oil;
|
|
|
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 ℃;
for 0.25h;
methyl iodide;
In
N,N-dimethyl-formamide; mineral oil;
for 0.25h;
|
85 mg
|
-
-
67-66-3,8013-54-5
chloroform
-
-
56-37-1
N-benzyl-N,N,N-triethylammonium chloride
-
-
61086-04-2
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol
-
-
61380-02-7
4-(methoxymethyl)-N-phenyl-1-(phenylmethyl)-4-piperidinamine
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide; dimethyl sulfate;
In
methanol; water; benzene;
|
|
|
With
sodium hydroxide; dimethyl sulfate;
In
methanol; ice-water; benzene;
|
61380-02-7 Upstream products
-
61086-04-2
4-(N-phenylamino)-1-phenylmethyl-4-piperidinylmethanol
-
74-88-4
methyl iodide
-
67-66-3
chloroform
-
56-37-1
N-benzyl-N,N,N-triethylammonium chloride
61380-02-7 Downstream products
-
61086-12-2
1-benzyl-4-[N-(1-oxopropyl)-N-phenylamino]-4-(methoxymethyl)piperidine
-
61086-13-3
N-[1-benzyl-4-(methoxymethyl)-4-piperidyl]-N-phenylpropionamide oxalate
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