(5alpha)-17-(cyclobutylmethyl)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one

  • CasNo:64643-71-6
  • purity:99%
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Details

Factory Sells Best Quality (5alpha)-17-(cyclobutylmethyl)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one 64643-71-6 with GMP standards

  • Molecular Formula: C22H27 N O4
  • Molecular Weight: 369.461

64643-71-6 Relevant articles

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Olofson,R.A.,Pepe,J.P.

, p. 1575 - 1578 (1977)

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N-alkyl-14-hydroxymorphinans and derivatives

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, (2008/06/13)

There is provided a novel and high yield...

64643-71-6 Process route

17-cyclobutanecarbonyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one
64643-72-7

17-cyclobutanecarbonyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one

17-cyclobutylmethyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one
64643-71-6

17-cyclobutylmethyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: TsOH / benzene
2: (i) LiAlH4 , THF, (ii) H+
With toluene-4-sulfonic acid; In benzene;
17-cyclobutanecarbonyl-4,5α-epoxy-6,6-ethanediyldioxy-3-methoxy-morphinan-14-ol
64801-00-9

17-cyclobutanecarbonyl-4,5α-epoxy-6,6-ethanediyldioxy-3-methoxy-morphinan-14-ol

17-cyclobutylmethyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one
64643-71-6

17-cyclobutylmethyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one

Conditions
Conditions Yield
Multistep reaction; (i) LiAlH4, THF, (ii) H+;

64643-71-6 Upstream products

  • 64801-00-9
    64801-00-9

    17-cyclobutanecarbonyl-4,5α-epoxy-6,6-ethanediyldioxy-3-methoxy-morphinan-14-ol

  • 64643-72-7
    64643-72-7

    17-cyclobutanecarbonyl-4,5α-epoxy-14-hydroxy-3-methoxy-morphinan-6-one

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