1H-Dibenzo[de,h]quinoline-2,7-dione

  • CasNo：31293-07-9
  • purity：99%
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Details

Reputable manufacturer supply 1H-Dibenzo[de,h]quinoline-2,7-dione 31293-07-9 in stock with high standard

  • Molecular Formula:C16H9 N O2
  • Molecular Weight:247.253
  • Vapor Pressure:8.04E-17mmHg at 25°C 
  • Melting Point:248 °C (decomp) 
  • Boiling Point:650.8°C at 760 mmHg 
  • PKA:10.36±0.20(Predicted) 
  • Flash Point:284.7°C 
  • PSA：50.19000 
  • Density:1.43g/cm3 
  • LogP:3.15180 

1H-Dibenzo[de,h]quinoline-2,7-dione(Cas 31293-07-9) Usage

1H-Dibenzo[de,h]quinoline-2,7-dione

+ A naturally occurring alkaloid
+ Heterocyclic compound
+ Found in various plant species (e.g. Indian beech tree and Australian brush cherry)

Ellipticine

+ Has potential anti-tumor properties
+ Demonstrated antitumor and mutagenic effects
+ Studied for its potential as a chemotherapeutic agent
+ Exerts its effects by intercalating into DNA and inhibiting topoisomerase activity
+ Ultimately leads to cell death

Research

+ Ongoing studies on the use of ellipticine in cancer treatment
+ Shows promise as a potential anti-cancer drug

General Description

1H-Dibenzo[de,h]quinoline-2,7-dione, also known as ellipticine, is a naturally occurring alkaloid that has been used in cancer research due to its potential anti-tumor properties. It is a heterocyclic compound that is found in various plant species such as the Indian beech tree (Ochrosia elliptica) and the Australian brush cherry (Syzygium smithii). Ellipticine has demonstrated antitumor and mutagenic effects, and has been studied for its potential as a chemotherapeutic agent. It is believed to exert its effects by intercalating into DNA and inhibiting topoisomerase activity, ultimately leading to cell death. Research on the use of ellipticine in cancer treatment is ongoing, and it shows promise as a potential anti-cancer drug.

InChI:InChI=1/C16H9NO2/c18-13-8-9-4-3-7-12-14(9)15(17-13)10-5-1-2-6-11(10)16(12)19/h1-8H,(H,17,18)

31293-07-9 Relevant articles

REACTION OF α-HALOGENO- AND α-NITROANTHRAQUINONES WITH THE ANIONS OF CH ACIDS. II. PERI-CYCLIZATION IN THE REACTION WITH NITRILES

Gorelik, M. V.,Titova, S. P.,Kanor, M. A.

, p. 1858 - 1864 (2007/10/02)

As a result of hydrolysis of the nitrile...

TAUTOMERISM AND ACID-BASE CHARACTERISTICS OF 2-HYDROXY-1-AZABENZANTHRONES

Mikhailova, T. A.,Zaitsev, B. E.,Gorelik, M. V.

, p. 703 - 710 (2007/10/02)

In solutions of 2-hydroxy-1-azabenzanthr...

31293-07-9 Process route

2-hydroxy-3-ethoxycarbonyl-7H-dibenzo<de,h>quinolin-7-one
120346-99-8

2-hydroxy-3-ethoxycarbonyl-7H-dibenzoquinolin-7-one

2-hydroxy-7H-dibenzo<de,h>quinolin-7-one
31293-07-9

2-hydroxy-7H-dibenzoquinolin-7-one

Conditions
Conditions Yield
With sulfuric acid; at 170 ℃; for 6h;
73%
1-(cyanoethoxycarbonylmethyl)anthraquinone
120346-94-3

1-(cyanoethoxycarbonylmethyl)anthraquinone

2-hydroxy-7H-dibenzo<de,h>quinolin-7-one
31293-07-9

2-hydroxy-7H-dibenzoquinolin-7-one

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 80 percent / 75percent aq. H2SO4 / 0.25 h / 110 °C
2: 73 percent / 60percent aq. H2SO4 / 6 h / 170 °C
With sulfuric acid;
Multi-step reaction with 3 steps
1: 1.) conc. H2SO4, 2.) H2O / 1.) 20 deg C, 5 min
2: 94 percent / 1 N aq. NaOH / 0.25 h
3: 73 percent / 60percent aq. H2SO4 / 6 h / 170 °C
With sodium hydroxide; sulfuric acid; water;

31293-07-9 Upstream products

  • 120346-99-8
    120346-99-8

    2-hydroxy-3-ethoxycarbonyl-7H-dibenzoquinolin-7-one

  • 120346-94-3
    120346-94-3

    1-(cyanoethoxycarbonylmethyl)anthraquinone

  • 152027-94-6
    152027-94-6

    1-(carbamoylethoxycarbonylmethyl)anthraquinone

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